1st Trimester Screening Test in Kolkata
What Is 1st Trimester Screening?
At Fetomat Wellness in Kolkata, our comprehensive 1st-trimester scan provides expectant parents with reliable early understandings about their baby’s development.
Why is 1st Trimester Screening Recommended?
Our specialised first-trimester screening doctors in Kolkata provide expert guidance through this crucial stage, help parents understand the results, and plan proper follow-up care if required.
Tests Included in 1st Trimester Screening?

Nuchal Translucency (NT) Scan
NT scan is an ultrasound that measures the fluid at the back of the baby’s neck. A high thickness measurement may indicate a higher risk of chromosomal abnormalities, such as
- Down syndrome (Trisomy 21)
- Edwards syndrome (Trisomy 18)
- Patau syndrome (Trisomy 13)

Blood Test
The blood tests are done at 10 weeks but can also be performed until 13 weeks and 6 days. These tests measure two specific hormones:
- Pregnancy-associated plasma protein-A (PAPP-A)
- Beta-human chorionic gonadotropin (hCG)
- Placental growth factor (PLGF) — optional for better accuracy
If the result finds any abnormal level, it may suggest an increased risk of genetic conditions.

Cell-Free Fetal DNA Screening or NIPT
Through this test, doctors test the maternal blood to examine DNA fragments of a baby, including issues with sex chromosomes. However, this test does not detect structural congenital problems such as spina bifida or abdominal wall abnormalities.
All these tests provide an overall risk assessment. If results suggest a higher risk, your doctor may recommend further diagnostic tests like amniocentesis or chorionic villus sampling (CVS).
Who Should Get 1st Trimester Screening?







What to Expect During 1st Trimester Screening?

Ultrasound
A painless scan checks fetal development and studies nuchal translucency.

Blood Sample
A small blood sample is taken to assess hormone and protein levels.

Results
Combined findings evaluate the risk of chromosomal abnormalities. Your doctor will explain the results and suggest further steps if necessary.
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Ideal Time for 1st Trimester Screening
The optimal window for screening is between 11 weeks and 13 weeks, 6 days of pregnancy. This timing ensures the most accurate measurements of NT and biochemical markers in your blood.